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Pfizer, after discontinuing its initial danuglipron candidate due to safety concerns in April 2025, re-entered the race through a $10 billion acquisition of clinical-stage biotech Metsera in November 2025, securing a next-generation obesity pipeline [43]

Mathieu M, et al

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This pathology is accompanied by the accumulation of misfolded -Syn, forming eosinophilic inclusion bodies known as Lewy bodies, alongside neuroinflammation